It would be insane if it not only looked like a Mario game, but Mario himself even appeared only to be thrown out of the way by Wario, I don't think they'd go that far since I always imagined it being something in-engine, but could you imagine
I'd love them to do something like the old Wario Land commercials where you think it's a trailer for a Mario game and BAM! Wario jumpscare! It'd be such a cool homage.
As everyone has said, greed is definitely his most defining thing first and foremost, but Wario being so driven is something that defines him to me. He gets his ass beat in SML2 and decides that if he can't steal a castle... he might as well go...
I think he has many stand out features, his fatness, his strength, his greed, and how absurd he is.
But I think Nintendo makes him stand out about his encompasses.