I will always respond, no matter what! Because if I don't people will think I'm a douche. Unless it's somebody on DA requesting something, then I will not respond (most of the time.)
I'm still glad I made all those body swap pictures, it made somebody give me a core membership on DA which came in real handy, now I can make polls, show more pictures and my a custom welcome page. Awesome, just because of some pictures I get 3 month of core! It's awesome to have. Now that I have it I never wanna leave it!