You think that given their prior experience with making Metroid and 2D platforming in DKC, Retro could try their hand at a 2D Metroid?
Also, what are the odds of Anthony Higgs being a potential P2? (Pffffft)
Probably low chance and specifically it doesn't have to be Retrostudios to do the job. Nintendo could probably get another developer as it happened with Other M with Team Ninja. We'll probably never get to see Anthony Higgs. Not like it matters since Anthony Higgs sucks, he's an annoying character and he does nothing. He's just there to be there basically. Doesn't add to the story and occasionally pops out here and there like the fight between Samus and Ridley. Would much rather he not come back at all.